Asthma data set

Recurrent asthma attacks in children

Asthma is occurring more and more frequently in very young children (between 6 and 24 months). Therefore, a new application of an existing anti-allergic drug is administered to children who are at higher risk to develop asthma in order to prevent it. A prevention trial is set up with such children randomised to placebo or drug, and the asthma events that developed over time are recorded in a diary. Typically, a patient has more than one asthma event. The different events are thus clustered within a patient and are ordered in time. This ordering can be taken into account in the model. Such data can be presented in different formats, but here, we choose to use the calendar time representation. In the calendar time representation, the time at risk for a particular event is the time from the end of the previous event (asthma attack) to the start of the next event (start of the next asthma attack). In describing recurrent event data, we need a somewhat more complex data structure to keep track of the sequence of events within a patient. A particular patient has different periods at risk during the total observation period which are separated either by an asthmatic event that lasts one or more days or by a period in which the patient was not under observation. The start and end of each such risk period is required, together with the status indicator to denote whether the end of the risk period corresponds to an asthma attack or not.

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First ten observations:

Patid,Begin,End,Status,Drug,Fevent
1,0,15,1,0,1
1,22,90,1,0,0
1,96,325,1,0,0
1,329,332,1,0,0
1,338,369,1,0,0
1,370,412,1,0,0
1,418,422,1,0,0
1,426,474,1,0,0
1,477,526,1,0,0
1,530,600,0,0,0
Reacties op de inhoud: Luc.Duchateau@ugent.be. Laatste wijziging January 29 2008 17:06:01.
Faculteit Diergeneeskunde - BiometrieBiometrie
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